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IV Course on Molecular Evolution, Phylogenetics, Phylogenomics and Adaptation.
This course aims at providing the necessary background to understand the basic concepts from comparative and evolutionary biology that are frequently used in molecular biology and bioinformatics analyses.
More than 30 years ago Theodosius Dobzhansky stated: “Nothing in biology makes sense if not seen under the light of evolution". Nowadays even the simplest bioinformatics analysis involves the comparison of sequences from different species to determine the function of a novel sequence. Moreover, there are many molecular evolution or phylogenetic concepts that are used in chemistry and biology labs with varying knowledge from the theory and practice. Some examples include: homology, similarity, evolutionary rate, branch attraction, lineage effect, neutralism, positive selection, phylogram, rooted tree, etc. This course aims to provide the necessary bakground to understand the basic concepts of evolutionary and comparative biology that are commonly used in molecular biology and bioinformatics.
This 5-days course involves theoretical and computer practicals sessions that address different problems of evolutio nary biology and hypothesis testing. The course includes a session of phylogenomic analysis and functional annotation, including most recent developments in these areas. Attendees will get familiar with, among others, the following tools: Phylip, Phyml, PAML, TreePuzzle, MrBayes, Modeltest, ProTest, jModelTest programs, all of them integrated in the Phylemon web-server. The course is intended for professional biologists or chemists whose work involves the analyses of biological sequences.
Mon, 15/06/2009 (All day) - Fri, 19/06/2009 (All day)
Centro de Investigación Príncipe Felipe, CIPF, Valencia, Spain